Parvolex infusion

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This is reproduced directly from this publication: http://www.bmj.com/content/342/bmj.d2218/T2.expansion.html


Parvolex infusion - Note a limit of 110kg is used when calculating doses for obese patients
Dosing schedule based on weight Volume of infusion For 70kg adult For 110kg adult For 140mg adult
150 mg/kg over 15 minutes 200mL 10.5 g 16.5 g 16.5 g
50 mg/kg over next 4 hours 500mL 3.5 g 5.5 g 5.5 g
100 mg/kg over next 16 hours 1000mL 7 g 11 g 11 g
Total dose (300 mg/kg in 20 hours) X 21 g 33 g 33 g

This is to be used in those deemed high risk from paracetamol overdose. Please see paracetamol overdose nomogram

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